Erratum to: ppiPre: predicting protein-protein interactions by combining heterogeneous features
نویسندگان
چکیده
منابع مشابه
Predicting Protein-Protein Interactions Using Relational Features
Motivation: Proteins play a fundamental role in every process within the cell. Understanding how proteins interact, and the functional units they are part of, is important to furthering our knowledge of the entire biological process. There has been a growing amount of work, both experimetal and computational, on determining the protein-protein interaction network. Recently researchers have had ...
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This chapter presents applications of machine learning to predicting protein-protein interactions (PPI) in Saccharomyces cerevisiae. Several supervised inductive learning methods have been developed that treat this task as a classification problem over candidate links in a PPI network – a graph whose nodes represent proteins and whose arcs represent interactions. Most such methods use feature e...
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Most cellular functions involve proteins' features based on their physical interactions with other partner proteins. Sketching a map of protein-protein interactions (PPIs) is therefore an important inception step towards understanding the basics of cell functions. Several experimental techniques operating in vivo or in vitro have made significant contributions to screening a large number of pro...
متن کاملPredicting Protein Interactions by Brownian Dynamics Simulations
We present a newly adapted Brownian-Dynamics (BD)-based protein docking method for predicting native protein complexes. The approach includes global BD conformational sampling, compact complex selection, and local energy minimization. In order to reduce the computational costs for energy evaluations, a shell-based grid force field was developed to represent the receptor protein and solvation ef...
متن کاملDiscovering Domains Mediating Protein Interactions
Background: Protein-protein interactions do not provide any direct information regarding the domains within the proteins that mediate the interactions. The majority of proteins are multi domain proteins and the interaction between them is often defined by the pairs of their domains. Most of the former studies focus only on interacting domain pairs. However they do not consider the in...
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ژورنال
عنوان ژورنال: BMC Systems Biology
سال: 2015
ISSN: 1752-0509
DOI: 10.1186/s12918-015-0196-5